Manchester United sit in third position heading into the derby on Sunday and Jamie Carragher believes Robin van Persie and Angel di Maria won’t start the clash at Old Trafford.
Louis van Gaal's side are favourites going into this match against City after wins over Tottenham, Liverpool and Aston Villa.
It’s a vital match for both sides, especially for United who know a win on the day will see them install a four point gap over the Premier League champions Manchester City.
However, when former Liverpool defender Carragher was quizzed about Van Persie who is back in training at United, he told Sky Sports: "I don’t think he’ll [Van Persie] start in the Manchester derby.
"United look like they have got a settled system with Wayne Rooney at the top of the pitch now. Rooney has got the shirt, even though Van Persie has a great relationship with Van Gaal.
"On the back of the World Cup it took Van Persie a while for him to get going and get back in the team, and I think it has been difficult for him this season and last season with injury.
"He suffered a lot at Arsenal with injuries, but his first season at United seemed to be without trouble. It hasn’t been the same since.
"If Van Gaal just wants to play with one striker it would be Wayne Rooney, so Van Persie will have to wait his turn."
And regarding Manchester United's record summer signing Angel di Maria, the Liverpool legend said: "I don’t think he’ll start either. Van Gaal shows that when he picks a team and wins he picks the same team again.
"I expected Di Maria to come back in against Liverpool, but they kept Juan Mata and he got the two goals.
"I think the form United are in at the moment he will keep the same team - he seems that type of coach.
"He has said that big personalities or the cost of a player does not matter, and at the moment the team is playing well, and I’m sure he’ll stick with it."