Louis van Gaal's side travel to Newcastle to face the Magpies after a 2-0 win over Sunderland at Old Trafford and ex-Gunner Paul Merson thinks Newcastle could get a positive point from the clash.
Manchester United currently sit in fourth place in the Premier League table and will be hoping they can leave the North-East with three points.
But, Sky Sports pundit Merson reckons John Carver's side will make things difficult for United at St James' Park.
"Manchester United played better the other day against Sunderland, but there’s still something big missing there," he told Sky Sports.
"It’s another opportunity for Angel di Maria to defy the critics. His confidence is so low, and you feel for someone when you can see it so clearly.
"This is the hardest league in the world and his struggles have proved it. He played in a team at Real Madrid who beat everyone, and the opposition often gave up at 2-0 or 3-0, and now he’s come over here and found it tough.
"Newcastle are comfortably mid-table, and despite the win against Villa perhaps masking how the Toon fans are feeling, I think they'll get a positive point here."
The Arsenal legend predicted a 1-1 draw.